Hemophilic Arthropathy in Children: Pathophysiology, Diagnosis and Management

Arthropathy is a serious and common problem in patients with hemophilia impairing the patient’s quality of life seriously. The most commonly affected joints hemophilic arthropathy are knees, ankles elbows. Even single bleeding could cause devastating effects to synovium, cartilage also subchondral bones. Ultrasound magnetic resonance imaging have been advocated for studying damage. Prophylaxis has demonstrated as standard choice management prevent development. Primary prophylaxis starting at early years age very important hemorrhages but secondary adolescents significant success rates. As duration exposure blood increases joint cavity, degeneration matrix resultant loss increase, so aspiration hematoma from plays an role prevention disease progression. Synovectomy may be required cases where does not recurrent hemorrhages. purpose synovectomy either medical or surgical methods remove problematic synovium progression arthropathy. Medical (synoviorthesis) two basic types; radiosynovectomy chemical former one appearing more effective about 85% If all these measures fail progressive damage, open arthroscopic synovectomy, arthrodesis even arthroplasty necessary. Here we tried summarize pathological mechanism, diagnosis children.